Pan-phosphatidylinositol 3-kinase inhibition with buparlisib in patients with relapsed or refractory non-Hodgkin lymphoma

Activation of the phosphatidylinositol 3-kinase/mechanistic target of rapamycin pathway plays a role in the pathogenesis of non-Hodgkin lymphoma. This multicenter, open-label phase 2 study evaluated buparlisib (BKM120), a pan-class I phosphatidylinositol 3-kinase inhibitor, in patients with relapsed...

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Detalhes bibliográficos
Publicado no:Haematologica
Main Authors: Younes, Anas, Salles, Gilles, Martinelli, Giovanni, Bociek, Robert Gregory, Barrigon, Dolores Caballero, Barca, Eva González, Turgut, Mehmet, Gerecitano, John, Kong, Oliver, Pisal, Chaitali Babanrao, Tavorath, Ranjana, Kim, Won Seog
Formato: Artigo
Idioma:Inglês
Publicado em: Ferrata Storti Foundation 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5709110/
https://ncbi.nlm.nih.gov/pubmed/28971900
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2017.169656
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