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Characterizing the heterogeneity of tumor tissues from spatially resolved molecular measures

BACKGROUND: Tumor heterogeneity can manifest itself by sub-populations of cells having distinct phenotypic profiles expressed as diverse molecular, morphological and spatial distributions. This inherent heterogeneity poses challenges in terms of diagnosis, prognosis and efficient treatment. Conseque...

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Publicat a:PLoS One
Autors principals: Graf, John F., Zavodszky, Maria I.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5708750/
https://ncbi.nlm.nih.gov/pubmed/29190747
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0188878
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