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From [(11)C]CO(2) to [(11)C]amides: a rapid one-pot synthesis via the Mitsunobu reaction
A novel amide synthesis methodology is described using amines, CO(2) and Grignard reagents and Mitsunobu reagents. The method was applied to carbon-11 radiochemistry to label amides using cyclotron-produced [(11)C]CO(2). The synthetic utility of the one-pot labelling methodology was demonstrated by...
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| Pubblicato in: | Chem Commun (Camb) |
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| Autori principali: | , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Royal Society of Chemistry
2017
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5708528/ https://ncbi.nlm.nih.gov/pubmed/28447672 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c7cc01407d |
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