Covariate adjustment had similar benefits in small and large randomised controlled trials

OBJECTIVE: Covariate adjustment is a standard statistical approach in the analysis of randomised controlled trials. We aimed to explore whether the benefit of covariate adjustment on statistical significance and power differed between small and large trials, where chance imbalance in prognostic fact...

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Vydáno v:J Clin Epidemiol
Hlavní autoři: Thompson, Douglas D., Lingsma, Hester F., Whiteley, William N., Murray, Gordon D., Steyerberg, Ewout W.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2014
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5708297/
https://ncbi.nlm.nih.gov/pubmed/25497979
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jclinepi.2014.11.001
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