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Metabolomic effects of CeO(2), SiO(2) and CuO metal oxide nanomaterials on HepG2 cells

BACKGROUND: To better assess potential hepatotoxicity of nanomaterials, human liver HepG2 cells were exposed for 3 days to five different CeO(2) (either 30 or 100 μg/ml), 3 SiO(2) based (30 μg/ml) or 1 CuO (3 μg/ml) nanomaterials with dry primary particle sizes ranging from 15 to 213 nm. Metabolomic...

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Detalhes bibliográficos
Publicado no:Part Fibre Toxicol
Main Authors: Kitchin, Kirk T., Stirdivant, Steve, Robinette, Brian L., Castellon, Benjamin T., Liang, Xinhua
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5708175/
https://ncbi.nlm.nih.gov/pubmed/29187207
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12989-017-0230-4
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