Gut microbiota-mediated generation of saturated fatty acids elicits inflammation in the liver in murine high-fat diet-induced steatohepatitis

BACKGROUND: The gut microbiota plays crucial roles in the development of non-alcoholic steatohepatitis (NASH). However, the precise mechanisms by which alterations of the gut microbiota and its metabolism contributing to the pathogenesis of NASH are not yet fully elucidated. METHODS: Mice were fed w...

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Detalhes bibliográficos
Publicado no:BMC Gastroenterol
Main Authors: Yamada, Shoji, Kamada, Nobuhiko, Amiya, Takeru, Nakamoto, Nobuhiro, Nakaoka, Toshiaki, Kimura, Masaki, Saito, Yoshimasa, Ejima, Chieko, Kanai, Takanori, Saito, Hidetsugu
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5708095/
https://ncbi.nlm.nih.gov/pubmed/29187142
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12876-017-0689-3
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