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Obesity reversibly depletes the basal cell population and enhances mammary epithelial cell estrogen receptor alpha expression and progenitor activity

BACKGROUND: Obesity is correlated with an increased risk for developing postmenopausal breast cancer. Since obesity rates continue to rise worldwide, it is important to understand how the obese microenvironment influences normal mammary tissue to increase breast cancer risk. We hypothesized that obe...

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Detalhes bibliográficos
Publicado no:Breast Cancer Res
Main Authors: Chamberlin, Tamara, D’Amato, Joseph V., Arendt, Lisa M.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5707907/
https://ncbi.nlm.nih.gov/pubmed/29187227
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13058-017-0921-7
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