WNT Inhibitory Activity of Malus Pumila miller cv Annurca and Malus domestica cv Limoncella Apple Extracts on Human Colon-Rectal Cells Carrying Familial Adenomatous Polyposis Mutations

Inhibitors of the Wingless-related Integration site (WNT)/β-catenin pathway have recently been under consideration as potential chemopreventive agents against Familial Adenomatous Polyposis (FAP). This autosomal-dominant syndrome is caused by germline mutations in the gene coding for the protein APC...

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Vydáno v:Nutrients
Hlavní autoři: Riccio, Gennaro, Maisto, Maria, Bottone, Sara, Badolati, Nadia, Rossi, Giovanni Battista, Tenore, Gian Carlo, Stornaiuolo, Mariano, Novellino, Ettore
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2017
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5707734/
https://ncbi.nlm.nih.gov/pubmed/29156563
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/nu9111262
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