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Hyperpolarization of amino acid derivatives in water for biological applications
We report on the successful synthesis and hyperpolarization of N-unprotected α-amino acid ethyl propionate esters and extensively, on an alanine derivative hyperpolarized by PHIP (4.4 ± 1.0% (13)C-polarization), meeting required levels for in vivo detection. Using water as solvent increases biocompa...
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| Publicado no: | Chem Sci |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Royal Society of Chemistry
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5707458/ https://ncbi.nlm.nih.gov/pubmed/29218193 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c5sc00503e |
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