EMC3 coordinates surfactant protein and lipid homeostasis required for respiration

Adaptation to respiration at birth depends upon the synthesis of pulmonary surfactant, a lipid-protein complex that reduces surface tension at the air-liquid interface in the alveoli and prevents lung collapse during the ventilatory cycle. Herein, we demonstrated that the gene encoding a subunit of...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Tang, Xiaofang, Snowball, John M., Xu, Yan, Na, Cheng-Lun, Weaver, Timothy E., Clair, Geremy, Kyle, Jennifer E., Zink, Erika M., Ansong, Charles, Wei, Wei, Huang, Meina, Lin, Xinhua, Whitsett, Jeffrey A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5707157/
https://ncbi.nlm.nih.gov/pubmed/29083321
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI94152
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