GLIS3 is indispensable for TSH/TSHR-dependent thyroid hormone biosynthesis and follicular cell proliferation

Deficiency in Krüppel-like zinc finger transcription factor GLI-similar 3 (GLIS3) in humans is associated with the development of congenital hypothyroidism. However, the functions of GLIS3 in the thyroid gland and the mechanism by which GLIS3 dysfunction causes hypothyroidism are unknown. In the cur...

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Bibliografiska uppgifter
I publikationen:J Clin Invest
Huvudupphovsmän: Kang, Hong Soon, Kumar, Dhirendra, Liao, Grace, Lichti-Kaiser, Kristin, Gerrish, Kevin, Liao, Xiao-Hui, Refetoff, Samuel, Jothi, Raja, Jetten, Anton M.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Clinical Investigation 2017
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5707155/
https://ncbi.nlm.nih.gov/pubmed/29083325
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI94417
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