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Farnesyl phenolic enantiomers as natural MTH1 inhibitors from Ganoderma sinense

Cancer cells are more addictive to MTH1 than normal cells because of their dysfunctional redox regulations. MTH1 plays an important role to maintain tumor cell survival, while it is not indispensable for the growth of normal cells. Farnesyl phenols having a coumaroyl substitution are rather uncommon...

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書目詳細資料
發表在:Oncotarget
Main Authors: Gao, Ya, Zhu, Lihan, Guo, Jing, Yuan, Ting, Wang, Liqing, Li, Hua, Chen, Lixia
格式: Artigo
語言:Inglês
出版: Impact Journals LLC 2017
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5707067/
https://ncbi.nlm.nih.gov/pubmed/29221173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.21430
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