Subependymal giant cell astrocytomas in Tuberous Sclerosis Complex have consistent TSC1/TSC2 biallelic inactivation, and no BRAF mutations

Subependymal giant cell astrocytomas (SEGAs) are rare, low-grade glioneuronal brain tumors that occur almost exclusively in patients with tuberous sclerosis complex (TSC). Though histologically benign, SEGAs can lead to serious neurological complications, including hydrocephalus, intractable seizure...

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Dades bibliogràfiques
Publicat a:Oncotarget
Autors principals: Bongaarts, Anika, Giannikou, Krinio, Reinten, Roy J., Anink, Jasper J., Mills, James D., Jansen, Floor E., Spliet, G.M Wim, den Dunnen, Willfred F.A., Coras, Roland, Blümcke, Ingmar, Paulus, Werner, Scholl, Theresa, Feucht, Martha, Kotulska, Katarzyna, Jozwiak, Sergiusz, Buccoliero, Anna Maria, Caporalini, Chiara, Giordano, Flavio, Genitori, Lorenzo, Söylemezoğlu, Figen, Pimentel, José, Nellist, Mark, Schouten-van Meeteren, Antoinette Y.N., Nag, Anwesha, Mühlebner, Angelika, Kwiatkowski, David J., Aronica, Eleonora
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals LLC 2017
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5707039/
https://ncbi.nlm.nih.gov/pubmed/29221145
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.20764
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