UCP2 overexpression enhanced glycolysis via activation of PFKFB2 during skin cell transformation

Uncoupling protein 2 (UCP2) is an inner mitochondrial membrane transporter which is often upregulated in human cancers. However, how this anion transporter affects tumorigenesis is not well understood. Using the skin cell transformation JB6 model, we demonstrated that UCP2 overexpression activated p...

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Dades bibliogràfiques
Publicat a:Oncotarget
Autors principals: Sreedhar, Annapoorna, Petruska, Petra, Miriyala, Sumitra, Panchatcharam, Manikandan, Zhao, Yunfeng
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals LLC 2017
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5707038/
https://ncbi.nlm.nih.gov/pubmed/29221144
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.20762
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