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Production of N(α)-acetyl Tα1-HSA through in vitro acetylation by RimJ
Thymosin alpha 1 (Tα1) is an important immunomodulating agent with various clinical applications. The natural form of Tα1 is N(α)-acetylated, which was supposed to be related to in vivo stability of the hormone. In this study, fusion protein Tα1-HSA was constructed and expressed in Pichia pastoris....
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| Gepubliceerd in: | Oncotarget |
|---|---|
| Hoofdauteurs: | , , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
Impact Journals LLC
2017
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5707018/ https://ncbi.nlm.nih.gov/pubmed/29221124 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.20259 |
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