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Production of N(α)-acetyl Tα1-HSA through in vitro acetylation by RimJ

Thymosin alpha 1 (Tα1) is an important immunomodulating agent with various clinical applications. The natural form of Tα1 is N(α)-acetylated, which was supposed to be related to in vivo stability of the hormone. In this study, fusion protein Tα1-HSA was constructed and expressed in Pichia pastoris....

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Bibliografiske detaljer
Udgivet i:Oncotarget
Main Authors: Chen, Jing, Li, Haibin, Wang, Tao, Sun, Shuyang, Liu, Jia, Chen, Jianhua
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5707018/
https://ncbi.nlm.nih.gov/pubmed/29221124
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.20259
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