VEGF-induced intracellular Ca(2+) oscillations are down-regulated and do not stimulate angiogenesis in breast cancer-derived endothelial colony forming cells

Endothelial colony forming cells (ECFCs) represent a population of truly endothelial precursors that promote the angiogenic switch in solid tumors, such as breast cancer (BC). The intracellular Ca(2+) toolkit, which drives the pro-angiogenic response to VEGF, is remodelled in tumor-associated ECFCs...

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Udgivet i:Oncotarget
Main Authors: Lodola, Francesco, Laforenza, Umberto, Cattaneo, Fabio, Ruffinatti, Federico Alessandro, Poletto, Valentina, Massa, Margherita, Tancredi, Richard, Zuccolo, Estella, Khdar, Dlzar Alì, Riccardi, Alberto, Biggiogera, Marco, Rosti, Vittorio, Guerra, Germano, Moccia, Francesco
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2017
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5707017/
https://ncbi.nlm.nih.gov/pubmed/29221123
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.20255
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