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Low circulating levels of the mitochondrial-peptide hormone SHLP2: novel biomarker for prostate cancer risk

CONTEXT: Mitochondrial DNA mutations and dysfunction are associated with prostate cancer (PCa). Small humanin-like peptide-2 (SHLP2) is a novel mitochondrial-encoded peptide and an important mitochondrial retrograde signaling molecule. OBJECTIVE: To determine whether serum SHLP2 concentration is ass...

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Détails bibliographiques
Publié dans:Oncotarget
Auteurs principaux: Xiao, Jialin, Howard, Lauren, Wan, Junxiang, Wiggins, Emily, Vidal, Adriana, Cohen, Pinchas, Freedland, Stephen J.
Format: Artigo
Langue:Inglês
Publié: Impact Journals LLC 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5706922/
https://ncbi.nlm.nih.gov/pubmed/29212276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.20134
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