CR6-interacting factor 1 inhibits invasiveness by suppressing TGF-β-mediated epithelial-mesenchymal transition in hepatocellular carcinoma

CR6-interacting factor 1 (CRIF1) regulates cell cycle progression and the DNA damage response. Here, we show that CRIF1 expression is decreased in hepatocellular carcinoma (HCC) tissues and positively correlates with patients’ survival. In vitro, down-regulation of CRIF1 promotes HCC cell proliferat...

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Podrobná bibliografie
Vydáno v:Oncotarget
Hlavní autoři: Zhuang, Runzhou, Lu, Di, Zhuo, Jianyong, Zhang, Xuanyu, Wang, Kun, Wei, Xuyong, Wei, Qiang, Wang, Wei, Xie, Haiyang, Zhou, Lin, Xu, Xiao, Zheng, Shusen
Médium: Artigo
Jazyk:Inglês
Vydáno: Impact Journals LLC 2017
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5706910/
https://ncbi.nlm.nih.gov/pubmed/29212264
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.21925
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