CR6-interacting factor 1 inhibits invasiveness by suppressing TGF-β-mediated epithelial-mesenchymal transition in hepatocellular carcinoma

CR6-interacting factor 1 (CRIF1) regulates cell cycle progression and the DNA damage response. Here, we show that CRIF1 expression is decreased in hepatocellular carcinoma (HCC) tissues and positively correlates with patients’ survival. In vitro, down-regulation of CRIF1 promotes HCC cell proliferat...

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Publicado en:Oncotarget
Autores principales: Zhuang, Runzhou, Lu, Di, Zhuo, Jianyong, Zhang, Xuanyu, Wang, Kun, Wei, Xuyong, Wei, Qiang, Wang, Wei, Xie, Haiyang, Zhou, Lin, Xu, Xiao, Zheng, Shusen
Formato: Artigo
Lenguaje:Inglês
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5706910/
https://ncbi.nlm.nih.gov/pubmed/29212264
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.21925
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