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Growth differentiation factor 15 mediates epithelial mesenchymal transition and invasion of breast cancers through IGF-1R-FoxM1 signaling

Expression of the inflammatory cytokine growth differentiation factor 15 (GDF15) is significantly elevated in many tumor types in association with epithelial mesenchymal transition (EMT), drug resistance, and progressive disease. However, few studies have examined GDF15 expression, signaling, or fun...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Peake, Bridgette F., Eze, Siobhan M., Yang, Lily, Castellino, Robert C., Nahta, Rita
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5706882/
https://ncbi.nlm.nih.gov/pubmed/29212236
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.21765
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