RNAscope in situ hybridization confirms mRNA integrity in formalin-fixed, paraffin-embedded cancer tissue samples

Immunohistochemistry remains the overwhelming technique of choice for test biomarker evaluation in both clinical or research settings when using formalin-fixed, paraffin embedded tissue sections. However, validations can be complex with significant issues about specificity, sensitivity and reproduci...

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Bibliographische Detailangaben
Veröffentlicht in:Oncotarget
Hauptverfasser: Bingham, Victoria, McIlreavey, Leanne, Greene, Christine, O’Doherty, Edwina, Clarke, Rebecca, Craig, Stephanie, Salto-Tellez, Manuel, McQuaid, Stephen, Lewis, Claire, James, Jacqueline
Format: Artigo
Sprache:Inglês
Veröffentlicht: Impact Journals LLC 2017
Schlagworte:
Research Paper: Pathology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5706804/
https://ncbi.nlm.nih.gov/pubmed/29212158
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.21851
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