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Structure of a functional ribonucleoprotein pseudouridine synthase bound to a substrate RNA

Box H/ACA small nucleolar and Cajal body ribonucleoprotein particles comprise the most complex pseudouridine synthases and are essential for ribosome and spliceosome maturation. The multistep and multicomponent-mediated enzyme mechanism remains only partially understood. Here we report a crystal str...

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Detalhes bibliográficos
Publicado no:Nat Struct Mol Biol
Main Authors: Liang, Bo, Zhou, Jing, Kahen, Elliot, Terns, Rebecca M, Terns, Michael P, Li, Hong
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5706466/
https://ncbi.nlm.nih.gov/pubmed/19478803
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.1624
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