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Sirt1 interaction with active Smad2 modulates transforming growth factor-β regulated transcription

BACKGROUND: The simplicity of Transforming Growth Factor ß (TGFβ) signaling pathway, linear and non-amplified, hardly sustains its variety of responses. This is often justified by the complex regulation showed by Smad proteins, TGFβ signaling intracellular transducers, object of post-translational m...

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Detalhes bibliográficos
Publicado no:Cell Commun Signal
Main Authors: García-Vizcaíno, Eva María, Liarte, Sergio, Alonso-Romero, José Luis, Nicolás, Francisco José
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5706420/
https://ncbi.nlm.nih.gov/pubmed/29187201
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12964-017-0205-y
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