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Smad4 SUMOylation is essential for memory formation through upregulation of the skeletal myopathy gene TPM2
BACKGROUND: Smad4 is a critical effector of TGF-β signaling that regulates a variety of cellular functions. However, its role in the brain has rarely been studied. Here, we examined the molecular mechanisms underlying the post-translational regulation of Smad4 function by SUMOylation, and its role i...
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| Publicat a: | BMC Biol |
|---|---|
| Autors principals: | , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
BioMed Central
2017
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5706330/ https://ncbi.nlm.nih.gov/pubmed/29183317 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12915-017-0452-9 |
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