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Smad4 SUMOylation is essential for memory formation through upregulation of the skeletal myopathy gene TPM2
BACKGROUND: Smad4 is a critical effector of TGF-β signaling that regulates a variety of cellular functions. However, its role in the brain has rarely been studied. Here, we examined the molecular mechanisms underlying the post-translational regulation of Smad4 function by SUMOylation, and its role i...
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| 出版年: | BMC Biol |
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| 主要な著者: | , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
BioMed Central
2017
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5706330/ https://ncbi.nlm.nih.gov/pubmed/29183317 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12915-017-0452-9 |
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