RAC3 influences the chemoresistance of colon cancer cells through autophagy and apoptosis inhibition

BACKGROUND: RAC3 coactivator overexpression has been implicated in tumorigenesis, contributing to inhibition of apoptosis and autophagy. Both mechanisms are involved in resistance to treatment with chemotherapeutic agents. The aim of this study was to investigate its role in chemoresistance of color...

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Bibliografski detalji
Izdano u:Cancer Cell Int
Glavni autori: Rubio, María Fernanda, Lira, María Cecilia, Rosa, Francisco Damián, Sambresqui, Adrían Dario, Salazar Güemes, María Cecilia, Costas, Mónica Alejandra
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2017
Teme:
Primary Research
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5706160/
https://ncbi.nlm.nih.gov/pubmed/29209153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12935-017-0483-x
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