RAC3 influences the chemoresistance of colon cancer cells through autophagy and apoptosis inhibition

BACKGROUND: RAC3 coactivator overexpression has been implicated in tumorigenesis, contributing to inhibition of apoptosis and autophagy. Both mechanisms are involved in resistance to treatment with chemotherapeutic agents. The aim of this study was to investigate its role in chemoresistance of color...

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Publicat a:Cancer Cell Int
Autors principals: Rubio, María Fernanda, Lira, María Cecilia, Rosa, Francisco Damián, Sambresqui, Adrían Dario, Salazar Güemes, María Cecilia, Costas, Mónica Alejandra
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2017
Matèries:
Primary Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5706160/
https://ncbi.nlm.nih.gov/pubmed/29209153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12935-017-0483-x
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