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Epigenetic modifiers in immunotherapy: a focus on checkpoint inhibitors

Immune surveillance should be directed to suppress tumor development and progression, involving a balance of coinhibitory and costimulatory signals that amplify immune response without overwhelming the host. Immunotherapy confers durable clinical benefit in ‘immunogenic tumors’, whereas in other tum...

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Detalhes bibliográficos
Publicado no:Immunotherapy
Main Authors: Terranova-Barberio, Manuela, Thomas, Scott, Munster, Pamela N
Formato: Artigo
Idioma:Inglês
Publicado em: Future Medicine Ltd 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5705793/
https://ncbi.nlm.nih.gov/pubmed/27197539
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/imt-2016-0014
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