Decorin and Biglycan Are Necessary for Maintaining Collagen Fibril Structure, Fiber Realignment, and Mechanical Properties of Mature Tendons

The small leucine-rich proteoglycans (SLRPs), decorin and biglycan, are key regulators of collagen fibril and matrix assembly. The goal of this work was to elucidate the roles of decorin and biglycan in tendon homeostasis. Our central hypothesis is that decorin and biglycan expression in the mature...

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Publicat a:Matrix Biol
Autors principals: Robinson, Kelsey A., Sun, Mei, Barnum, Carrie E., Weiss, Stephanie N., Huegel, Julianne, Shetye, Snehal S., Lin, Linda, Saez, Daniel, Adams, Sheila M., Iozzo, Renato V., Soslowsky, Louis J., Birk, David E.
Format: Artigo
Idioma:Inglês
Publicat: 2017
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5705405/
https://ncbi.nlm.nih.gov/pubmed/28882761
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.matbio.2017.08.004
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