The SARS-CoV Fusion Peptide Forms an Extended Bipartite Fusion Platform that Perturbs Membrane Order in a Calcium-Dependent Manner

Coronaviruses (CoVs) are a major infectious disease threat and include the pathogenic human pathogens of zoonotic origin: severe acute respiratory syndrome CoV (SARS-CoV) and Middle East respiratory syndrome CoV (MERS-CoV). Entry of CoVs into host cells is mediated by the viral spike (S) protein, wh...

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Bibliographic Details
Published in:J Mol Biol
Main Authors: Lai, Alex L., Millet, Jean K., Daniel, Susan, Freed, Jack H., Whittaker, Gary R.
Format: Artigo
Language:Inglês
Published: Elsevier Ltd. 2017
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5705393/
https://ncbi.nlm.nih.gov/pubmed/29056462
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2017.10.017
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