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Insights into Protein Misfolding and Aggregation enabled by Solid-State NMR Spectroscopy

The aggregation of proteins and peptides into a variety of insoluble, and often non-native, aggregated states plays a central role in many devastating diseases. Analogous processes undermine the efficacy of polypeptide-based biological pharmaceuticals, but are also being leveraged in the design of b...

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Detalhes bibliográficos
Publicado no:Solid State Nucl Magn Reson
Autor principal: van der Wel, Patrick C.A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5705391/
https://ncbi.nlm.nih.gov/pubmed/29035839
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ssnmr.2017.10.001
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