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Insights into Protein Misfolding and Aggregation enabled by Solid-State NMR Spectroscopy
The aggregation of proteins and peptides into a variety of insoluble, and often non-native, aggregated states plays a central role in many devastating diseases. Analogous processes undermine the efficacy of polypeptide-based biological pharmaceuticals, but are also being leveraged in the design of b...
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Publicado no: | Solid State Nucl Magn Reson |
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Autor principal: | |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2017
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5705391/ https://ncbi.nlm.nih.gov/pubmed/29035839 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ssnmr.2017.10.001 |
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