Midlife systemic inflammatory markers are associated with late-life brain volume: The ARIC study

OBJECTIVE: To clarify the temporal relationship between systemic inflammation and neurodegeneration, we examined whether a higher level of circulating inflammatory markers during midlife was associated with smaller brain volumes in late life using a large biracial prospective cohort study. METHODS:...

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Pubblicato in:Neurology
Autori principali: Walker, Keenan A., Hoogeveen, Ron C., Folsom, Aaron R., Ballantyne, Christie M., Knopman, David S., Windham, B. Gwen, Jack, Clifford R., Gottesman, Rebecca F.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Lippincott Williams & Wilkins 2017
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5705246/
https://ncbi.nlm.nih.gov/pubmed/29093073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/WNL.0000000000004688
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