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Broncho Vaxom (OM-85) modulates rhinovirus docking proteins on human airway epithelial cells via Erk1/2 mitogen activated protein kinase and cAMP

BACKGROUND: Bronchial epithelial cells (BEC) are primary target for Rhinovirus infection through attaching to cell membrane proteins. OM-85, a bacterial extract, improves recovery of asthma and COPD patients after viral infections, but only part of the mechanism was addressed, by focusing on defined...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Roth, Michael, Pasquali, Christian, Stolz, Daiana, Tamm, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5705076/
https://ncbi.nlm.nih.gov/pubmed/29182620
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0188010
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