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AMP-activated protein kinase: a key regulator of energy balance with many roles in human disease

The AMP-activated protein kinase (AMPK) is a sensor of cellular energy status that regulates cellular and whole body energy balance. A recent crystal structure has illuminated the complex regulatory mechanisms by which AMP and ADP cause activation of AMPK, involving phosphorylation by the upstream k...

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Detalhes bibliográficos
Publicado no:J Intern Med
Autor principal: Hardie, D. Grahame
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5705060/
https://ncbi.nlm.nih.gov/pubmed/24824502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/joim.12268
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