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A permutation approach to the assignment of the configuration to diastereomeric tetrads by comparison of experimental and ab initio calculated differences in NMR data

Scoring permutations of experimental chemical shift deviations and DFT/GIAO calculated deviations of isotropic shieldings for sets of four diastereomers can help to assign their relative configurations. This method was exercised on a set of diastereomeric Cinchona alkaloid derivatives, where (13)C N...

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Vydáno v:Beilstein J Org Chem
Hlavní autor: Boratyński, Przemysław J
Médium: Artigo
Jazyk:Inglês
Vydáno: Beilstein-Institut 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5704763/
https://ncbi.nlm.nih.gov/pubmed/29234475
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3762/bjoc.13.245
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