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PI3K/mTOR Inhibitors in the Treatment of Luminal Breast Cancer. Why, When and to Whom?

Estrogen receptor (ER) signaling represents the main driver of tumor growth and survival in luminal breast cancer (BC). Despite the efficacy of endocrine agents, many patients with luminal BC do not respond to endocrine therapy and many others develop endocrine resistance over time, due to the activ...

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Detalhes bibliográficos
Publicado no:Breast Care (Basel)
Main Authors: Schettini, Francesco, Buono, Giuseppe, Trivedi, Meghana V., De Placido, Sabino, Arpino, Grazia, Giuliano, Mario
Formato: Artigo
Idioma:Inglês
Publicado em: S. Karger GmbH 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5704698/
https://ncbi.nlm.nih.gov/pubmed/29234247
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000481657
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