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Development and clinical application of anti-HER2 monoclonal and bispecific antibodies for cancer treatment

HER2-targeted immunotherapy consists of monoclonal antibodies (e.g. trastuzumab, pertuzumab), bispecific antibodies (e.g. MM-111, ertumaxomab) and activated T cells armed with anti-HER2 bispecific antibody (HER2Bi-aATC). Trastuzumab is a classic drug for the treatment of HER2 positive metastatic bre...

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Detalhes bibliográficos
Publicado no:Exp Hematol Oncol
Main Authors: Yu, Shengnan, Liu, Qian, Han, Xinwei, Qin, Shuang, Zhao, Weiheng, Li, Anping, Wu, Kongming
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5704598/
https://ncbi.nlm.nih.gov/pubmed/29209558
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40164-017-0091-4
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