Structural analyses of the MazEF4 toxin-antitoxin pair in Mycobacterium tuberculosis provide evidence for a unique extracellular death factor

The bacterial toxin-antitoxin MazEF system in the tuberculosis (TB)-causing bacterium Mycobacterium tuberculosis is activated under unfavorable conditions, including starvation, antibiotic exposure, and oxidative stress. This system contains the ribonucleolytic enzyme MazF and has emerged as a promi...

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Vydáno v:J Biol Chem
Hlavní autoři: Ahn, Do-Hwan, Lee, Ki-Young, Lee, Sang Jae, Park, Sung Jean, Yoon, Hye-Jin, Kim, Soon-Jong, Lee, Bong-Jin
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2017
Témata:
Protein Structure and Folding
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5704469/
https://ncbi.nlm.nih.gov/pubmed/28972145
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.807974
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