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Protective effect of zoledronic acid on articular cartilage and subchondral bone of rabbits with experimental knee osteoarthritis

Subchondral bone reabsorption and remodeling are responsible for the initiation and progression of osteoarthritis (OA). Zoledronic acid (ZOL), a third-generation bisphosphonate (BIS), is an inhibitor of bone reabsorption. However, the intervention effect of ZOL on OA has not been fully characterized...

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Detalhes bibliográficos
Publicado no:Exp Ther Med
Main Authors: She, Guorong, Zhou, Ziqi, Zha, Zhengang, Wang, Fei, Pan, Xiaoting
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5704325/
https://ncbi.nlm.nih.gov/pubmed/29201194
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/etm.2017.5135
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