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Protective effect of zoledronic acid on articular cartilage and subchondral bone of rabbits with experimental knee osteoarthritis

Subchondral bone reabsorption and remodeling are responsible for the initiation and progression of osteoarthritis (OA). Zoledronic acid (ZOL), a third-generation bisphosphonate (BIS), is an inhibitor of bone reabsorption. However, the intervention effect of ZOL on OA has not been fully characterized...

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Dades bibliogràfiques
Publicat a:Exp Ther Med
Autors principals: She, Guorong, Zhou, Ziqi, Zha, Zhengang, Wang, Fei, Pan, Xiaoting
Format: Artigo
Idioma:Inglês
Publicat: D.A. Spandidos 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5704325/
https://ncbi.nlm.nih.gov/pubmed/29201194
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/etm.2017.5135
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