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Leukotriene B(4) receptor 2 gene polymorphism (rs1950504, Asp196Gly) leads to enhanced cell motility under low-dose ligand stimulation
Recently, single-nucleotide polymorphisms (SNPs) in G-protein-coupled receptors (GPCRs) have been suggested to contribute to physiopathology and therapeutic effects. Leukotriene B(4) receptor 2 (BLT2), a member of the GPCR family, plays a critical role in the pathogenesis of several inflammatory dis...
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Publicado no: | Exp Mol Med |
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Main Authors: | , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Nature Publishing Group
2017
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5704194/ https://ncbi.nlm.nih.gov/pubmed/29170475 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emm.2017.192 |
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