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Leukotriene B(4) receptor 2 gene polymorphism (rs1950504, Asp196Gly) leads to enhanced cell motility under low-dose ligand stimulation

Recently, single-nucleotide polymorphisms (SNPs) in G-protein-coupled receptors (GPCRs) have been suggested to contribute to physiopathology and therapeutic effects. Leukotriene B(4) receptor 2 (BLT2), a member of the GPCR family, plays a critical role in the pathogenesis of several inflammatory dis...

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Detalhes bibliográficos
Publicado no:Exp Mol Med
Main Authors: Jang, Jae-Hyun, Wei, Jun-Dong, Kim, Minsup, Kim, Joo-Young, Cho, Art E, Kim, Jae-Hong
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5704194/
https://ncbi.nlm.nih.gov/pubmed/29170475
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emm.2017.192
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