Generation of an osteoblast-based artificial niche that supports in vitro B lymphopoiesis

B lymphocytes are produced from hematopoietic stem cells (HSCs) through the highly ordered process of B lymphopoiesis, which is regulated by a complex network of cytokines, chemokines and cell adhesion molecules derived from the hematopoietic niche. Primary osteoblasts function as an osteoblastic ni...

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Detalhes bibliográficos
Publicado no:Exp Mol Med
Main Authors: Yu, Jiyeon, Choi, Seunga, Kim, Hyeonkyeong, Lee, Nari, Yun, Hyeongseok, Kim, Sumi, Jeong, Seong-Tae, Rho, Jaerang
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5704192/
https://ncbi.nlm.nih.gov/pubmed/29170473
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emm.2017.189
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