Post-zygotic genomic changes in glutamate and dopamine pathway genes may explain discordance of monozygotic twins for schizophrenia

BACKGROUND: Monozygotic twins are valuable in assessing the genetic vs environmental contribution to diseases. In the era of complete genome sequences, they allow identification of mutational mechanisms and specific genes and pathways that offer predisposition to the development of complex diseases...

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Bibliographic Details
Published in:Clin Transl Med
Main Authors: Castellani, C. A., Melka, M. G., Gui, J. L., Gallo, A. J., O’Reilly, R. L., Singh, S. M.
Format: Artigo
Language:Inglês
Published: Springer Berlin Heidelberg 2017
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Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5704032/
https://ncbi.nlm.nih.gov/pubmed/29181591
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40169-017-0174-1
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