MiR-16-5p mediates a positive feedback loop in EV71-induced apoptosis and suppresses virus replication

Enterovirus 71 (EV71) is the predominant causative pathogen of hand-foot-and-mouth disease (HFMD). Contrary to other HFMD-causing enterovirus, EV71 can lead to severe neurological complications, even death. MicroRNAs (miRNAs) are small non-coding RNAs that constitute the largest family of gene regul...

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Vydáno v:Sci Rep
Hlavní autoři: Zheng, Caishang, Zheng, Zhenhua, Sun, Jianhong, Zhang, Yuan, Wei, Chunyu, Ke, Xianliang, Liu, Yan, Deng, Li, Wang, Hanzhong
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2017
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5703983/
https://ncbi.nlm.nih.gov/pubmed/29180670
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-16616-7
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