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The Dual Role of Cellular Senescence in Developing Tumors and Their Response to Cancer Therapy

Cellular senescence describes an irreversible growth arrest characterized by distinct morphology, gene expression pattern, and secretory phenotype. The final or intermediate stages of senescence can be reached by different genetic mechanisms and in answer to different external and internal stresses....

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Dettagli Bibliografici
Pubblicato in:Front Oncol
Autori principali: Schosserer, Markus, Grillari, Johannes, Breitenbach, Michael
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5703792/
https://ncbi.nlm.nih.gov/pubmed/29218300
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2017.00278
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