Host-based lipid inflammation drives pathogenesis in Francisella infection

Mass spectrometry imaging (MSI) was used to elucidate host lipids involved in the inflammatory signaling pathway generated at the host–pathogen interface during a septic bacterial infection. Using Francisella novicida as a model organism, a bacterial lipid virulence factor (endotoxin) was imaged and...

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Dettagli Bibliografici
Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Scott, Alison J., Post, Julia Maria, Lerner, Raissa, Ellis, Shane R., Lieberman, Joshua, Shirey, Kari Ann, Heeren, Ron M. A., Bindila, Laura, Ernst, Robert K.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2017
Soggetti:
Biological Sciences
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5703311/
https://ncbi.nlm.nih.gov/pubmed/29109289
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1712887114
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