Directed evolution of SecB chaperones toward toxin-antitoxin systems

SecB chaperones assist protein export in bacteria. However, certain SecB family members have diverged to become specialized toward the control of toxin-antitoxin (TA) systems known to promote bacterial adaptation to stress and persistence. In such tripartite TA-chaperone (TAC) systems, the chaperone...

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Dettagli Bibliografici
Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Sala, Ambre Julie, Bordes, Patricia, Ayala, Sara, Slama, Nawel, Tranier, Samuel, Coddeville, Michèle, Cirinesi, Anne-Marie, Castanié-Cornet, Marie-Pierre, Mourey, Lionel, Genevaux, Pierre
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2017
Soggetti:
Biological Sciences
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5703295/
https://ncbi.nlm.nih.gov/pubmed/29114057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1710456114
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