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Anticancer effect of dentatin and dentatin-hydroxypropyl-β-cyclodextrin complex on human colon cancer (HT-29) cell line

INTRODUCTION: Dentatin (DEN) (5-methoxy-2, 2-dimethyl-10-(1, 1-dimethyl-2propenyl) dipyran-2-one), a natural compound present in the roots of Clausena excavata Burm f, possesses pro-apoptotic and antiproliferative effects in various cancer cells. Because of its hydrophobicity, it is believed that it...

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Detalhes bibliográficos
Publicado no:Drug Des Devel Ther
Main Authors: AL-Abboodi, Ashwaq Shakir, Rasedee, Abdullah, Abdul, Ahmad Bustamam, Taufiq-Yap, Yun Hin, Alkaby, Wafaa Abd Alwahed, Ghaji, Mostafa Saddam, Waziri, Peter M, Al-Qubaisi, Mothanna Sadiq
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5703156/
https://ncbi.nlm.nih.gov/pubmed/29200826
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S147626
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