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Statistical Performance of Image Cytometry for DNA, Lipids, Cytokeratin, & CD45 in a Model System for Circulation Tumor Cell Detection

Detection of circulating tumor cells (CTCs) in a blood sample is limited by the sensitivity and specificity of the biomarker panel used to identify CTCs over other blood cells. In this work, we present Bayesian theory that shows how test sensitivity and specificity set the rarity of cell that a test...

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Detalhes bibliográficos
Publicado no:Cytometry A
Main Authors: Futia, Gregory L., Schlaepfer, Isabel R., Qamar, Lubna, Behbakht, Kian, Gibson, Emily A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5703074/
https://ncbi.nlm.nih.gov/pubmed/28608985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cyto.a.23144
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