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Time-course, negative-stain electron microscopy–based analysis for investigating protein–protein interactions at the single-molecule level
Several biophysical approaches are available to study protein–protein interactions. Most approaches are conducted in bulk solution, and are therefore limited to an average measurement of the ensemble of molecular interactions. Here, we show how single-particle EM can enrich our understanding of prot...
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| Publicado no: | J Biol Chem |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5702678/ https://ncbi.nlm.nih.gov/pubmed/28972148 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.808352 |
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