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An update on anticancer drug development and delivery targeting carbonic anhydrase IX
The expression of carbonic anhydrase (CA) IX is up-regulated in many types of solid tumors in humans under hypoxic and acidic microenvironment. Inhibition of CA IX enzymatic activity with selective inhibitors, antibodies or labeled probes has been shown to reverse the acidic environment of solid tum...
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| Publicado no: | PeerJ |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
PeerJ Inc.
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5702504/ https://ncbi.nlm.nih.gov/pubmed/29181278 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7717/peerj.4068 |
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