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Intermedin Ameliorates Atherosclerosis by Increasing Cholesterol Efflux Through the cAMP-PKA Pathway in Macrophage RAW264.7 Cell Line

BACKGROUND: The aim of this study was to explore the role of intermedin and its mechanism in cholesterol efflux of macrophage THP-1 and RAW264.7 cell lines in atherosclerosis (AS). MATERIAL/METHODS: ApoE−/− mice were fed with a high-fat diet, and the concentrations of total cholesterol (TC), triglyc...

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Détails bibliographiques
Publié dans:Med Sci Monit
Auteurs principaux: Liao, Hang, Wan, Shixi, Zhang, Xin, Shi, Di, Zhu, Xiaojiang, Chen, Xiaoping
Format: Artigo
Langue:Inglês
Publié: International Scientific Literature, Inc. 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5702107/
https://ncbi.nlm.nih.gov/pubmed/29146892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12659/MSM.907298
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