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Reversing thyroid-hormone-mediated repression of a HSV-1 promoter via computationally guided mutagenesis
Thyroid hormones (THs) and their DNA-binding nuclear receptors (TRs) direct transcriptional regulation in diverse ways depending on the host cell environment and specific promoter characteristics of TH-sensitive genes. This study sought to elucidate the impact on transcriptional repression of nucleo...
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| Veröffentlicht in: | J Cell Sci |
|---|---|
| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
The Company of Biologists Ltd
2017
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5702054/ https://ncbi.nlm.nih.gov/pubmed/28916515 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.204222 |
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