Combination Drug Therapy of Pioglitazone and D-cycloserine Attenuates Chronic Orofacial Neuropathic Pain and Anxiety by Improving Mitochondrial Function Following Trigeminal Nerve Injury

OBJECTIVES: The study aim was to determine how peripheral trigeminal nerve injury affects mitochondrial respiration and to test efficacy of combined treatment with two FDA approved drugs with potential for improving mitochondrial bioenergetics, pain and anxiety related behaviors in a chronic orofaci...

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Bibliografiska uppgifter
I publikationen:Clin J Pain
Huvudupphovsmän: Lyons, Danielle N., Zhang, Liping, Pandya, Jignesh D., Danaher, Robert J., Ma, Fei, Miller, Craig S., Sullivan, Patrick G., Sirbu, Cristian, Westlund, Karin N.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2018
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5701889/
https://ncbi.nlm.nih.gov/pubmed/28542026
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/AJP.0000000000000515
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